In-Cel 2.0 should be taken 20-30 minutes prior to training or competing. Like the original formula, In-Cel 2.0 does not contain any stimulants ie. caffeine so will not effect sleep in any way nor will it cause adrenal fatigue like most pre-workouts. In-Cel 2.0 will provide pure physical performance, strength and endurance. Highly recommended for all serious athletes.